Normal Saline Administration with Endotracheal Suction to Reduce Ventilator-Associated Pneumonia Risk in children: A Multicentre Randomised Controlled Effectiveness-Implementation Trial (NATIVE)
The overarching aim of this project is to test saline administration with endotracheal suction as a nurse-led VAP prevention strategy in the paediatric intensive care unit.
Our objectives are to:
- Determine whether saline administration, compared to no saline with endotracheal suction, leads to a decreased risk of VAP in mechanically ventilated children.
- Investigate the cost-effectiveness of saline administration compared to no saline;
- Better understand the context for future system-wide implementation
- Build nursing clinician researcher capacity in paediatric critical care