Normal Saline Administration with Endotracheal Suction to Reduce Ventilator-Associated Pneumonia Risk in children: A Multicentre Randomised Controlled Effectiveness-Implementation Trial (NATIVE)

Chief Investigator

Dr Jessica Schultz RN GCert (Specialist Paed) MApp Sci (Research) PhD

Academic Institution

The University of Queensland

Date of Endorsement

03/08/2022

Outline

The overarching aim of this project is to test saline administration with endotracheal suction as a nurse-led VAP prevention strategy in the paediatric intensive care unit.

Our objectives are to:

  1. Determine whether saline administration, compared to no saline with endotracheal suction, leads to a decreased risk of VAP in mechanically ventilated children.
  2. Investigate the cost-effectiveness of saline administration compared to no saline;
  3. Better understand the context for future system-wide implementation
  4. Build nursing clinician researcher capacity in paediatric critical care